Michele Baccarani Selected Research

nilotinib

10/2022	Treatment-free remission in chronic myeloid leukemia patients treated front-line with nilotinib: 10-year followup of the GIMEMA CML 0307 study.
1/2018	Health-related quality of life in patients with chronic myeloid leukemia receiving first-line therapy with nilotinib.
1/2018	Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.
10/2017	Physicians' attitude towards selection of second line therapy with nilotinib and dasatinib in chronic myeloid leukemia patients.
10/2016	Nilotinib 300 mg twice daily: an academic single-arm study of newly diagnosed chronic phase chronic myeloid leukemia patients.
1/2016	Rotation of nilotinib and imatinib for first-line treatment of chronic phase chronic myeloid leukemia.
1/2016	In chronic myeloid leukemia patients on second-line tyrosine kinase inhibitor therapy, deep sequencing of BCR-ABL1 at the time of warning may allow sensitive detection of emerging drug-resistant mutants.
11/2015	Nilotinib in patients with systemic mastocytosis: analysis of the phase 2, open-label, single-arm nilotinib registration study.
9/2015	Long-term outcome of a phase 2 trial with nilotinib 400 mg twice daily in first-line treatment of chronic myeloid leukemia.
4/2015	Phase 3 study of nilotinib vs imatinib in Chinese patients with newly diagnosed chronic myeloid leukemia in chronic phase: ENESTchina.

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Michele Baccarani Research Topics

Disease

132	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 11/2022 - 02/2002
33	Philadelphia Chromosome 01/2022 - 02/2002
24	Neoplasms (Cancer) 01/2017 - 04/2002
24	Multiple Myeloma 03/2012 - 04/2002
22	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 09/2002
18	Leukemia 01/2021 - 09/2002
18	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2020 - 05/2002
17	Lymphoma (Lymphomas) 12/2013 - 08/2002
14	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 06/2013 - 02/2002
11	Non-Hodgkin Lymphoma (Lymphosarcoma) 03/2011 - 02/2002
10	Hematologic Neoplasms (Hematological Malignancy) 01/2017 - 09/2003
10	Blast Crisis (Blast Phase) 10/2016 - 03/2003
8	Thrombocytopenia (Thrombopenia) 01/2016 - 02/2002
8	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 12/2011 - 03/2005
7	Neutropenia 01/2016 - 05/2003
7	Infections 06/2013 - 09/2004
6	Exanthema (Rash) 01/2022 - 02/2012
6	Chromosome Aberrations (Chromosome Abnormalities) 11/2019 - 10/2007
6	Pathologic Complete Response 02/2009 - 11/2002
5	Residual Neoplasm 01/2021 - 02/2002
5	Disease Progression 08/2015 - 03/2002
5	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 08/2015 - 03/2002
5	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 08/2011 - 05/2005
4	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 12/2013 - 05/2003
4	Hypereosinophilic Syndrome (Loeffler Endocarditis) 12/2013 - 02/2004
4	Acute Promyelocytic Leukemia 05/2011 - 11/2002
4	B-Cell Lymphoma (Lymphoma, B Cell) 03/2011 - 05/2003
4	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 11/2008 - 02/2002
4	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 02/2008 - 11/2003
3	Pleural Effusion (Pleural Effusions) 01/2018 - 02/2012
3	Pancreatitis 01/2016 - 12/2009
3	Arthralgia (Joint Pain) 01/2016 - 05/2003
3	Thrombosis (Thrombus) 09/2015 - 04/2009
3	Hodgkin Disease (Hodgkin's Disease) 01/2012 - 08/2002
3	Essential Thrombocythemia 04/2009 - 11/2004
3	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 09/2007 - 09/2005
3	Graft vs Host Disease (Graft-Versus-Host Disease) 02/2007 - 10/2003
2	Bronchiolitis Obliterans Syndrome 01/2022 - 06/2008
2	Hypertension (High Blood Pressure) 04/2017 - 01/2016
2	Systemic Mastocytosis 11/2015 - 10/2007
2	Diarrhea 11/2015 - 05/2012
2	Primary Myelofibrosis (Myelosclerosis) 08/2015 - 04/2009
2	Pdgfra-Associated Chronic Eosinophilic Leukemia 12/2013 - 08/2004
2	Edema (Dropsy) 05/2012 - 02/2012
2	Myalgia 05/2012 - 02/2012

Drug/Important Bio-Agent (IBA)

102	Imatinib Mesylate (Gleevec)FDA Link 01/2021 - 02/2002
65	Tyrosine Kinase InhibitorsIBA 01/2022 - 03/2004
26	nilotinib FDA Link 10/2022 - 06/2007
22	Rituximab (Mabthera)FDA Link 12/2013 - 02/2002
20	Dasatinib (BMS 354825)FDA Link 01/2018 - 11/2006
16	Phosphotransferases (Kinase)IBA 01/2021 - 06/2005
15	Pharmaceutical PreparationsIBA 01/2020 - 01/2004
14	Thalidomide (Thalomid)FDA Link 03/2012 - 03/2002
13	Proteins (Proteins, Gene)FDA Link 10/2019 - 04/2002
13	Interferon-alpha (Interferon Alfa)IBA 10/2010 - 03/2002
12	Dexamethasone (Maxidex)FDA LinkGeneric 03/2012 - 09/2002
11	bcr-abl Fusion ProteinsIBA 01/2011 - 02/2002
10	fludarabineIBA 12/2013 - 12/2003
8	Inosine Triphosphate (ITP)IBA 01/2013 - 02/2002
7	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2011 - 05/2004
6	ponatinibIBA 01/2022 - 09/2014
6	Etoposide (VP 16)FDA LinkGeneric 07/2020 - 08/2002
6	Cytarabine (Cytosar-U)FDA LinkGeneric 07/2020 - 11/2002
6	Mitoxantrone (Novantrone)FDA LinkGeneric 07/2020 - 07/2004
6	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2019 - 06/2003
6	Prednisone (Sone)FDA LinkGeneric 08/2010 - 09/2002
5	HomoharringtonineIBA 01/2016 - 07/2013
5	Bortezomib (Velcade)FDA Link 01/2015 - 08/2006
5	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2012 - 10/2004
5	Vincristine (Oncovin)FDA LinkGeneric 08/2010 - 05/2004
4	SteroidsIBA 01/2022 - 02/2004
4	Hemoglobins (Hemoglobin)IBA 11/2019 - 11/2003
4	Lipase (Acid Lipase)FDA Link 01/2016 - 12/2009
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2011 - 11/2002
4	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 05/2011 - 11/2002
4	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2010 - 05/2005
3	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2014 - 04/2009
3	TOPSIBA 01/2014 - 05/2012
3	EnzymesIBA 02/2013 - 12/2009
3	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2013 - 04/2007
3	DNA (Deoxyribonucleic Acid)IBA 06/2012 - 12/2008
3	InterferonsIBA 07/2011 - 03/2003
3	Yttrium-90IBA 08/2010 - 02/2008
3	ibritumomab tiuxetan (Zevalin)FDA Link 08/2010 - 02/2008
3	Ifosfamide FDA LinkGeneric 11/2008 - 08/2002
3	Epirubicin (Ellence)FDA LinkGeneric 11/2008 - 08/2002
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 10/2007 - 06/2005
2	Alanine Transaminase (SGPT)IBA 01/2022 - 01/2016
2	Busulfan (Busulfex)FDA Link 01/2014 - 04/2009
2	AntibodiesIBA 06/2013 - 05/2003

Therapy/Procedure

79	Therapeutics 11/2022 - 04/2002
26	Drug Therapy (Chemotherapy) 09/2011 - 02/2002
19	Stem Cell Transplantation 05/2013 - 04/2002
9	Autologous Transplantation 12/2011 - 05/2003
7	Transplantation 08/2010 - 09/2003
5	Hematopoietic Stem Cell Transplantation 01/2017 - 12/2006
5	Salvage Therapy 12/2013 - 04/2002
3	Splenectomy 06/2013 - 06/2008
3	Radioimmunotherapy 08/2010 - 02/2008
3	Radiotherapy 11/2007 - 07/2003